The role of Cdk4 in tumorigenesis and metastasis
Oncogenic mutations initiate tumorigenesis but angiogenesis is necessary for expansion of tumor mass.
Moreover, aurora kinases also function in tumorigenesis. Some small molecules targeting to aurora kinases were found to have significant roles in tumor inhibition.
Pl4ARF and E2F1 suppress human colorectal tumorigenesis
Objective To investigate the tumor angiogenesis in benign, borderline and malignant epithelial ovarian tumors and its relationship with the tumorigenesis.
Roles of Rho GTPases in tumorigenesis
NR4A2 and its splicing variants contribute to tumorigenesis and metastasis of gastric cancer
RASSF1A and its role in tumorigenesis
Effect of conjunction matrigel with MFP implantation on the tumorigenesis,proliferation,apoptosis and metastasis of breast cancer cells with different expression of Her2
Recent studies showed that ARF gene may play a role in tumorigenesis; the ARF gene promoter hypermethylation may be the principal mechanism in the inactivation of this gene.
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
Inhibition effect of silencing EGFR gene by RNAi on tumorigenesis of xenograft tumor of ovarian cancer
Role and characteristic of Bmi-1 in the nervous development and tumorigenesis
