It turns out that crack closure is the main reason for retardation, and crack tip blunting, crack deflection and strain-induced martensite would reinforce it.
This shows how vital better prevention is to blunting and turning back the epidemic.
There is blunting and flattening of villi with celiac disease, and in severe cases a loss of villi with flattening of the mucosa as seen here.
Effect-site concentration of remifentanil blunting tracheal intubation response during anesthesia induction with etomidate