This functioned as a selective bridge, permitting the passage of positively charged sodium ions, but not negatively charged chloride ions.
So, for example, if I have a sodium ion over here, and I have a chloride ion over here, where the distance from center to center r I'm denoting as r, this is nucleus to nucleus separation.
If one sodium ion is ejected from the cell in exchange for one external potassiumion, the pump is electroneutral.
Smaller sodium ions leave the glass, and larger potassium ions from the salt bath replace them.
By pumping positively charged potassium and sodium ions out of the cell, the number of negatively charged ions inside the cells rises.
Poisoning of water also resulted in an electrolyte imbalance that affects the concentration of sodium ions and trigger the onset hyponatremia.
